Boolean operators allow you to combine search terms:
By default, Entrez searches your text in "All fields", which looks for the text anywhere in the entry. So if you're getting irrelevant results, try limiting your text to a particular field.
Don't know what fields you can search for? Use the Advanced search.
1. Click on advanced beneath the search bar.
2. Click the drop down menu under Builder to see what fields are stored in gene records.
This is a comprehensive list of all fields you can search for. Fields will vary by database. Example shown here is for the Gene database.
Curation is the process of converting a GEO Series (GSExxx) to a GEO dataset (GDSxxxx).
A GEO Series (GSExxx) is all the experimental data submitted by the investigator. A GEO DataSet is a collection of comparable Samples processed using the same Platform and includes experimental variables. Both of these entries are searchable in the GEO DataSets Database, but advanced analysis features are available only for GEO DataSets. GEO2R is useful for analyzing uncurated datasets.
Whether the data in GEO DataSets is curated or not, you can still download the data.
Curated: on the right of the page under the heat map
Uncurated: at the end of the record
You can search GEO DataSets by:
To see the full list of options, go to the Advanced search
Available fields are listed in the drop down menus on the resulting page, and you can see what values are in these fields by clicking Show index list to the right of the search box.
After submitting your search, a list of results will appear with gene records that match your query. The results page is divided into 3 columns:
Use the filters on the left to limit your data set to certain entry types (red box), Organism (orange arrow), study type (blue box) or attribute name (purple box)
The records that meet your search criteria are in the center column. The display shows the title of the record, a description of the experiment, and the unique identifiers for the associated records, as well as links to external resources.
The far right column is the discovery column. It also contains links to other databases, and your search strategy (yellow box).
To get to an individual GEO DataSet record of interest, click on the title of the dataset (blue link to the right of the check box).
The result will appear in one of two ways, depending on whether it has been curated by NCBI staff or not.
Uncurated: data submitted by the investigator who generated the data. There are no native tools to analyze this data, but you can use GEO2R to analyze these data.